Preparation and Care of the Area Postrema-Lesioned Cat
作者:
ChedesterA. L.,
BakarichA. C.,
RabinB. M.,
BanksR. E.,
HadickC. L.,
期刊:
Journal of Investigative Surgery
(Taylor Available online 1989)
卷期:
Volume 2,
issue 3
页码: 253-262
ISSN:0894-1939
年代: 1989
DOI:10.3109/08941938909057431
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The area postrema (AP) is being widely studied to delineate its role in such varied functions as blood pressure regulation, conditioned taste aversion, water and energy balance, and radiation-induced emesis. This paper describes the preoperative preparation, surgical procedure, and postoperative care of cats kept long-term in which the AP was lesioned by electrocautery. A dorsal midline approach under gas anesthesia allowed access to selectively lesion the AP. Cats fully regained consciousness the same day and many became homeostutic within 24-48 h. Results of experiments using this model demonstrate the usefulness and effectiveness of the technique for model preparation.
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