Derived pulmonary capillary pressure changes after smoke inhalation in sheep
作者:
TSUKASA,
ISAGO KENTAROU,
FUJIOKA LILLIAN,
TRABER DAVID,
HERNDON DANIEL,
期刊:
Critical Care Medicine
(OVID Available online 1991)
卷期:
Volume 19,
issue 11
页码: 1407-1413
ISSN:0090-3493
年代: 1991
出版商: OVID
关键词: pulmonary edema;pulmonary circulation;pulmonary wedge pressure;pulmonary veins;smoke inhalation injury;burns, inhalation;cardiac output;hydrostatic pressure;osmotic pressure;thromboxanes;leukotrienes
数据来源: OVID
摘要:
Background and MethodsWe determined derived pulmonary capillary pressure and the longitudinal distribution of pulmonary vascular resistance in chronically instrumented sheep with inhalation injury by using analysis of pressure decay curves after pulmonary artery occlusion.ResultsThere was an increase in derived pulmonary capillary pressure and an increase in the lung lymph flow after smoke inhalation. The pulmonary vascular, arterial, and venous resistances increased significantly in the inhalation group. Pulmonary venous resistance increased proportionately more than pulmonary arterial resistance in the inhalation group. The plasma osmotic pressure-derived pulmonary capillary pressure gradient decreased to a greater extent in the inhalation group than in the control group.ConclusionsThe present experiments suggest that the estimates of derived pulmonary capillary pressure can predict filtration pressure better than pulmonary artery occlusion pressure. The derived pulmonary capillary pressure can be measured easily in man with a pulmonary arterial catheter.
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