Survival Analysis with Median Regression Models
作者:
Z. Ying,
S.H. Jung,
L.J. Wei,
期刊:
Journal of the American Statistical Association
(Taylor Available online 1995)
卷期:
Volume 90,
issue 429
页码: 178-184
ISSN:0162-1459
年代: 1995
DOI:10.1080/01621459.1995.10476500
出版商: Taylor & Francis Group
关键词: Accelerated failure time model;Censored data;Estimating function;Least absolute deviations;Quantile regression
数据来源: Taylor
摘要:
The median is a simple and meaningful measure for the center of a long-tailed survival distribution. To examine the covariate effects on survival, a natural alternative to the usual mean regression model is to regress the median of the failure time variable or a transformation thereof on the covariates. In this article we propose semiparametric procedures to make inferences for such median regression models with possibly censored observations. Our proposals can be implemented efficiently using a simulated annealing algorithm. Numerical studies are conducted to show the advantage of the new procedures over some recently developed methods for the accelerated failure time model, a special type of mean regression models in the survival analysis. The proposals discussed in the article are illustrated with a lung cancer data set.
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