Calcium phosphate materials containing alumina: Raman spectroscopical, histological, and ultrastructural study
作者:
A. Bertoluzza,
R. Simoni,
A. Tinti,
M. Morocutti,
V. Ottani,
A. Ruggeri,
期刊:
Journal of Biomedical Materials Research
(WILEY Available online 1991)
卷期:
Volume 25,
issue 1
页码: 23-38
ISSN:0021-9304
年代: 1991
DOI:10.1002/jbm.820250103
出版商: John Wiley&Sons, Inc.
数据来源: WILEY
摘要:
AbstractVariable alumina quantities were added to two types of calcium phosphate materials–hydroxyapatite ceramics with Ca/P = 1.67 and calcium metaphosphate glass with Ca/P = 1–in order to increase their mechanical properties. Raman spectroscopy shows that alumina interacts with the phosphate group of these materials, while thermomechanical analysis shows that their elastic modulus has a value similar to that of bone. Histological sections demonstrate that the surface in close contact with ceramic materials shows a good integration between bone and biomaterial. All ceramic specimens are penetrated by well‐stained, presumably glycoprotein, matrix, that consistently forms a thin network in close contact with the implant. After 6 weeks bone growing on both ceramic and glass shows signs of maturation with a lamellar structure and an apparently normal mineralization. In the case of the glass, inside this newly formed bone, were often observed two layers, the internal one showing a well defined lamellar stru
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