The karyotype of the male ofAgama ruderatashows 46 elements which can be distingushed into 24 large rod-shaped subtelocentric and 22 small dot-shaped chromosomes. The karyotype of the female ofA. ruderatais very similar to that of the male. No heteromorphic chromosomes are observed either in the male or the female. Sex chromosomes are not identified. The fundamental chromosome number comes out to be 46.