Interventions for rational drug use that are being applied in developing countries also need to be applied to practices and regions in the developed world. Some‘ground-breaking work’is taking place in some healthcare centres in the developing world; there is a lot we can learn from this work, says Dr David Henry from the University of Newcastle, Australia. Together with innovative methods for knowledge transfer, the following studies illustrate the‘ongoing South-North cross-fertilisation process’across borders.1