Quantitative mr imaging data in the evaluation of hepatic metastases during systemic chemotherapy
作者:
Andrea Giovagnoni,
Enrico Paci,
Filippo Terilli,
Riccardo Cellerino,
Andrea Piga,
期刊:
Journal of Magnetic Resonance Imaging
(WILEY Available online 1995)
卷期:
Volume 5,
issue 1
页码: 27-32
ISSN:1053-1807
年代: 1995
DOI:10.1002/jmri.1880050108
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Liver neoplasms, MR, 761.121411;Liver neoplasms, secondary, 761.33;Liver neoplasms, therapy
数据来源: WILEY
摘要:
AbstractTo identify changes induced by chemotherapy in hepatic metastases, 34 patients with metastases underwent magnetic resonance (MR) imaging before the start of systemic chemotherapy and monthly thereafter. The number, size, and morphologic patterns of the lesions and changes in quantitative parameters (signal‐to‐noise ratio [S/N], contrast‐to‐noise ratio, and signal intensity ratio) were evaluated and correlated with response to treatment and prognosis. After treatment, seven patients showed a partial response, 18 had stable disease, and nine had progressive disease. No relevant changes in the patterns of the lesions were observed. Quantitative data showed that patients with a good prognosis had an increase in S/N on T1‐weighted images and a relative decrease on T2‐weighted images; patients with a poor prognosis showed a decrease in S/N on T1‐weighted images and an increase on T2‐weighted images. The differences between patient groups were significant for both T1‐ and T2‐ weighted images. This study demonstrates the value of MR imaging in follow‐up of liver metastases and suggests the usefulness of quantit
点击下载:
PDF
(552KB)
返 回