Determination of Some Penicillin Derivativies Using High Performance Liquid Chromatography
作者:
KhierA. Aboul,
G. Blaschke,
M. El Sadek,
期刊:
Analytical Letters
(Taylor Available online 1984)
卷期:
Volume 17,
issue 14
页码: 1659-1666
ISSN:0003-2719
年代: 1984
DOI:10.1080/00032718408065339
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
A rapid, precise and selective method is described for determination of penicillin derivatives. Penicillin derivatives are separated from closely related degradation products by high performance liquid chromatography at ambient temperature using 10cm column packed with 5um Nucleosil RP18and buffered aqueous acetonitrile as mobile phase. The eluate is monitored at 254nm. The procedure is suitable for determination of 8 penicillin derivatives either in raw material or phamaceutical dosage forms.
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