Quantitative Determination of Some Pharmaceutical Veterinary Formulations Using Bromocresol Purple and Bromocresol Green
作者:
AlaaS. Amin,
期刊:
Analytical Letters
(Taylor Available online 1997)
卷期:
Volume 30,
issue 14
页码: 2503-2513
ISSN:0003-2719
年代: 1997
DOI:10.1080/00032719708001761
出版商: Taylor & Francis Group
关键词: Antiprotozoal drug;spectrophotometric determination;bromocresol purple;bromocresol green;pharmaceutical analysis
数据来源: Taylor
摘要:
A simple, sensitive, accurate and rapid spectrophotometric method for the determination of some anthelmintics that are used in veterinary medication is described, based on the formation of an ion pair complex with bromocresol purple (BCP) and bromocresol green (BCG). Drugs analyzed are piperazine hexahydrate, tetramisole hydrochloride and metronidazole. The drugs were determined either in pure powdered forms or in pharmaceutical formulations using the standard addition technique. The sensitivity, precision and accuracy of the method was discussed and the results compared with the official method of British Pharmacopoeia (B.P. 1993).
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