Hepatitis C in Chronic Renal Failure Patients
作者:
Ahmed Mitwalli,
Suleiman Al-Mohaya,
Jamal Al Wakeel,
Hazem El Gamal,
Vincent Rotimi,
Abdulkarim Al-Zeben,
Abdulkarim Al-Aska,
期刊:
American Journal of Nephrology
(Karger Available online 1992)
卷期:
Volume 12,
issue 5
页码: 288-291
ISSN:0250-8095
年代: 1992
DOI:10.1159/000168462
出版商: S. Karger AG
关键词: Dialysis;Hepatitis C acquisition;Renal failure
数据来源: Karger
摘要:
The occurrence of hepatitis C virus (HCV) infection amongst chronic renal failure (CRF) patients in our Nephrology Unit was investigated over a period of 1 year. A total of 71 patients was studied comprising 26 chronic haemodialysis (CHD) patients, 6 acute haemodialysis patients, 4 peritoneal dialysis patients and 35 CRF patients not on dialysis. Patients were screened before and after haemodialysis, and their baseline and postdialysis values of liver enzymes were determined. Eleven (15.5%) of the total 71 patients were HCV antibody positive. Analysis of the individual patient groups showed that 8 (30.7%) of the 26 CHD patients were positive for HCV. Our data showed a statistically significant relationship between seroconversion and duration of dialysis (p < 0.05). A high statistically significant (p < 0.0001) correlation was observed between the HCV antibodies and CRF. The relative risk of hepatitis C was about 22 times greater for those with CRF compared with the normal controls, which makes CRF an important risk factor. A high proportion of the HCV seroconverters had elevated liver enzyme (serum glutamic pyruvic transaminase). The data presented show a positive correlation between HCV seroconversion, CRF, duration on dialysis and elevated serum liver enzymes.
点击下载:
PDF
(938KB)
返 回