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Temperature Sensitivity of a Sindbis Virus Mutant Isolated from Persistently InfectedAedes aegyptiCell Culture

 

作者: Victor Stollar,   Joseph Peleg,   Thomas E. Shenk,  

 

期刊: Intervirology  （Karger Available online 1973）
卷期: Volume 2, issue 5-6  

页码: 337-344

 

ISSN:0300-5526

 

年代: 1973

 

DOI:10.1159/000149441

 

出版商: S. Karger AG

 

关键词: Sindbis virus mutant;Aedes aegypti cells;Persistent infection

 

数据来源: Karger

 

摘要:

SV-S, a cloned small plaque mutant of Sindbis virus derived from persistently infected Aedes aegypti cell cultures, was shown also to be an RNA+ temperature-sensitive mutant. It interfered with the replication of SV-W at the nonpermissive temperature as well as the permissive temperature, but did not depress net viral RNA synthesis in cells coinfected with SV-W.

 

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