Design of a Low‐Field NMR Spectrometer to Measure Bone Mineral
作者:
JOSEPH,
BATTOCLETTI THOMAS,
MYERS THOMAS,
KNOX CHARLES,
BROWN HUSAIN,
期刊:
Journal of Clinical Engineering
(OVID Available online 1990)
卷期:
Volume 15,
issue 6
页码: 479-488
ISSN:0363-8855
年代: 1990
出版商: OVID
关键词: Osteoporosis;Apatites, Bone Mineral, Wrist;Nuclear Magnetic Resonance;Magnetic Resonance Spectroscopy;Permanent Magnets
数据来源: OVID
摘要:
Nuclear magnetic resonance phosphorus spectroscopy has been proposed as a new method to measure the mineral content of bone as a diagnostic and monitoring tool for osteoporosis. Preliminary studies have been performed on a Nicolet NT-150 NMR Spectrometer, using a 3.5-T superconducting magnet. This paper describes the design and construction of a low-field spectrometer for the human wrist. The 0.3256-T steady magnetic field is provided by a well-shimmed small-size permanent magnet made of neodymium-iron-boron. An IBM-PC-compatible computer is used both as host and post-processor to an Analogic AN9100A NMR Spectrometer. The narrower spectral linewidth expected at the lower magnetic field is expected to help compensate for sensitivity loss due to the weaker magnetic field.
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