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Hybrid scanning transmission electron/scanning tunnelling microscope system for the preparation and investigation of biomolecules

 

作者: H. F. KNAPP,   R. WYSS,   R. HÄRING,   C. HENN,   R. GUCKENBERGER,   A. ENGEL,  

 

期刊: Journal of Microscopy  （WILEY Available online 1995）
卷期: Volume 177, issue 1  

页码: 31-42

 

ISSN:0022-2720

 

年代: 1995

 

DOI:10.1111/j.1365-2818.1995.tb03531.x

 

出版商: Blackwell Publishing Ltd

 

关键词: STM;STEM;STM tips;freeze‐drying;metal‐coatings;catalase

 

数据来源: WILEY

 

摘要:

SummaryA hybrid scanning transmission electron/scanning tunnelling microscope vacuum system is introduced, which allows freeze drying and metal coating of biological samples and their simultaneous observation by scanning transmission electron microscopy and scanning tunnelling microscopy (STM). Different metal coatings and STM tips were analysed to obtain the highest possible resolution for such a system. Bovine liver catalase was used as a test sample and the STM results are compared to a molecular scale model.

 

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