A study of aryl sulfonamide compounds for the selection of candidates for carcinogen bioassay
作者:
C. T. Helmes,
C. C. Sigman,
M. K. Doeltz,
E. Helmes,
D. Lent,
K. E. McCaleb,
A. Miller,
L. Swett,
期刊:
Journal of Environmental Science and Health . Part A: Environmental Science and Engineering
(Taylor Available online 1983)
卷期:
Volume 18,
issue 2
页码: 175-201
ISSN:0360-1226
年代: 1983
DOI:10.1080/10934528309375103
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
The class of aryl sulfonamides was studied in order to nominate chemicals to the Chemical Selection Working Group as candidates for carcinogenesis bioassay. After application of several qualifying criteria relating to previous, current, or planned carcinogenicity tests and to commercial significance, the preliminary candidate list of 189 chemicals was reduced to a list of 89 chemicals. Based upon consideration of both the suspicion of possible carcinogenic activity and evidence indicating potential exposure, the following five chemicals were nominated: sulfanilamide, sulfamethazine, sulfathiazole, sulfamethizole, and salicylazosulfapyridine.
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