Lymphocytic Hypophysitis in a Man Presenting with Hypercalcemia
作者:
Louis Novoa-Takara,
Marcia Cornford,
Cynthia Williams,
John Tayek,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 2001)
卷期:
Volume 321,
issue 3
页码: 206-208
ISSN:0002-9629
年代: 2001
出版商: OVID
关键词: Hypercalcemia;Adrenal insufficiency;Lymphocytic hypophysitis.
数据来源: OVID
摘要:
A 59-year-old man with a 30-year history of type 2 diabetes mellitus presented with fatigue, confusion, and weight loss over a 3-month period. He was found to be hypercalcemic (11.8 mg/dL) and dehydrated, and his hypercalcemia improved with intravenous fluids. While in the hospital, he developed hyponatremia, hypoglycemia, and hypotension. He was found to have a subnormal cortisol level of 2.3 &mgr;g/dL at baseline, which increased to only 5.6 &mgr;g/dL 60 minutes after a 250-&mgr;g corticotropin intravenous stimulation test. The patient developed pneumonia and adult respiratory distress syndrome and died of an acute myocardial infarction. During the autopsy, he was found to have lymphocytic hypophysitis with a severe reduction in corticotropin-producing anterior pituitary cells. No malignancy was identified at autopsy. He is the first male patient to be described in the literature who presented with hypercalcemia caused by lymphocytic hypophysitis.
点击下载:
PDF
(311KB)
返 回