Comparison of Symptomatic and Asymptomatic Reinfarctions after Small Subcortical Stroke
作者:
Hideo Tohgi,
Kenichi Chiba,
Hiroaki Takahashi,
Kenichi Tamura,
Kazuhiro Sasaki,
Hajime Suzuki,
期刊:
European Neurology
(Karger Available online 1994)
卷期:
Volume 34,
issue 3
页码: 140-146
ISSN:0014-3022
年代: 1994
DOI:10.1159/000117027
出版商: S. Karger AG
关键词: Symptomatic reinfarct;Asymptomatic reinfarct;Lacunar infarct;Risk factors;Platelet aggregability
数据来源: Karger
摘要:
We compared possible factors leading to symptomatic and asymptomatic reinfarcts in 207 patients an average of 2.1 years after their index athero-thrombotic stroke presenting with small subcortical infarcts. Symptomatic reinfarcts were mostly small infarcts in the perforating artery regions associated with angiographic evidence of atherosclerosis of parent arteries (large-artery disease), a high hematocrit, elevated fibrinogen and Lp(a) levels. They occurred with insufficient inhibition of platelet aggregability in patients receiving antiplatelet medication. In contrast, many asymptomatic reinfarcts were small perforator infarcts not associated with large-artery disease or cortical infarcts, and occurred in the absence of hematologic risk markers, and in spite of sufficient inhibition of platelet aggregability.
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