Treatment of Human Leptospira Infections with Semicillin (Ampicillin) or with Amoxil (Amoxycillin)
作者:
D. Münnich,
M. Lakatos,
期刊:
Chemotherapy
(Karger Available online 1976)
卷期:
Volume 22,
issue 6
页码: 372-380
ISSN:0009-3157
年代: 1976
DOI:10.1159/000221949
出版商: S. Karger AG
关键词: Treatment of human leptospirosis;Ampicillin;Amoxycillin;Good results
数据来源: Karger
摘要:
Ampicillin (Semicillin) and Amoxycillin (Amoxil) have a strong leptospirocidal effect in vitro and also in vivo. We have tested these drugs on 28 patients suffering from Leptospira infection. The patients generally received per os 3 g Ampicillin (Semicillin) or 2 g Amoxycillin (Amoxil) per day over a period of 6 days. In the groups treated with Ampicillin and Amoxycillin the average durations of fever during the treatment were 1.6 and 1.2 days, respectively. In the first group (Ampicillin) a ‘second wave of fever’ occurred in one case (5 %) and in the second group (Amoxycillin), in 0% (as compared to 22% after treatment with benzylpenicillin). On the basis of our experiences, Ampicillin and Amoxycillin are strongly recommended for the treatment of human Leptospira infecti
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