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Sequential comparison of two treatments in clinical trials:a decision theoretic approach based on randomized play-the-winner rule

 

作者: Uttam Bandyopadhyay,   Atanu Biswas,  

 

期刊: Sequential Analysis  （Taylor Available online 1997）
卷期: Volume 16, issue 1  

页码: 65-91

 

ISSN:0747-4946

 

年代: 1997

 

DOI:10.1080/07474949708836373

 

出版商: Marcel Dekker, Inc.

 

关键词: Play-the-winner rule;Urn model;Stopping rule;Risk function;Minimax rule

 

数据来源: Taylor

 

摘要:

In the context of comparing two treatments in clinical trials randomized play-the-winner rule is used with the goal of treating more patients by the better treatment On its basis we give two decision rules by introducing stopping rule Some performance characteristics of one of the decision rules are discussed and examined .A minimax rule is suggested Finally some exact and asymptotic properties of the decision rule is derived

 

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