Leukocyte chromosomes from parents of cytogenetically abnormal offspring: preliminary observations
作者:
R. Stallard,
N.R. Haney,
P.A. Frank,
P. Styron,
R.C. Juberg,
期刊:
Cytogenetic and Genome Research
(Karger Available online 1981)
卷期:
Volume 30,
issue 1
页码: 50-53
ISSN:1424-8581
年代: 1981
DOI:10.1159/000131588
出版商: S. Karger AG
数据来源: Karger
摘要:
The frequency of sporadic, hypermodal chromosomal spreads in cultures of leukocytes taken from the parents of aneuploids significantly exceeds that in comparison populations. Elimination of other possibilities suggests mitotic nondisjunction as the ultimate determinant for such spreads. This possibility requires that more attention be paid to the occurrence of hypermodal spreads, especially relative to the etiology of aneuploid concepti.
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