Etude Clinique Et Ferrccinetique D’Un Cas De Thrombccythemie Hemorragique Essentielle
作者:
FrühlingJ.,
WettendorffP.,
KraytmanM.,
HenryJ.,
期刊:
Acta Clinica Belgica
(Taylor Available online 1968)
卷期:
Volume 23,
issue 5
页码: 310-324
ISSN:1784-3286
年代: 1968
DOI:10.1080/17843286.1968.11716690
出版商: Taylor&Francis
数据来源: Taylor
摘要:
SummaryA new case of primary hemorrhagic thrombocythemia is presented, in which ferrokinetic studies were performed 3 times in different phases of the illness.The 84 years old patient fitted all the clinical and hematological criteria of these disease : repeated spontaneous hemorrhages, splenomegaly, persistent thrombocythemia, severe and prolonged anemia, leukocytes not in excess of 50.000 and a rich bone marrow with pronounced megakaryocytic preponderance.Radioactive phosporous treatment produced several remissions, but the patient died 2 years after the diagnosis was established, showing a transformation to acute monocytic leukemia.The quantitative determinations of iron kinetics in the hemorrhagic phase, in remission and in hematologic relapse showed an highly increased erythropoiesis despite of the existent anemia and an important ineffective erythropoiesis.Therefore, the authors feel that primary hemorrhagic thrombocythemia is a myeloproliferative disorder with a predominant platelet elevation.
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