Primary structure of ribosomal proteins S3 and S7 fromManduca sexta
作者:
H. Jiang,
Y. Wang,
M. R. Kanost,
期刊:
Insect Molecular Biology
(WILEY Available online 1996)
卷期:
Volume 5,
issue 1
页码: 31-38
ISSN:0962-1075
年代: 1996
DOI:10.1111/j.1365-2583.1996.tb00038.x
出版商: Blackwell Publishing Ltd
关键词: tobacco hornworm;ribosome;cDNA;AP endonuclease
数据来源: WILEY
摘要:
AbstractWe have isolated fromManduca sextafull‐length cDNAs encoding proteins homologous to human ribosomal proteins S3 and S7. These are the first ribosomal protein sequences obtained from non‐Dipteran insects.M, sextaribosomal protein S3 has a molecular mass of 26,715 Da. Ribosomal protein S7 has a mass 21,870 Da. Both are basic proteins, with abundant Lys and Arg residues that may interact with ribosomal RNA in the ribosome. Southern blot hybridization suggests the presence of single genes for both ribosomal proteins in theM. sextagenome. Alignments with other S3 and S7 sequences available in the database indicate regions of the ribosomal proteins that have been the most highly conserved in evolution and may point to important functional regions in the proteins. Ribosomal protein S3 appears to be more highly conserved than ribosomal protein S7. This may be due to greater constraints on the structure of S3 because of its dual functions in translation as a ribosomal protein and in DNA repair in the nucl
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