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Effect of Urinary Alkalinization on Renal Changes Produced by Cationic Albumin

 

作者: Terezila M. Coimbra,   Grazia DeGiacobbi,   Maria A. Gouveia,   João J. Lachat,   Ivan F. De Carvalho,  

 

期刊: Nephron  （Karger Available online 1984）
卷期: Volume 38, issue 4  

页码: 261-266

 

ISSN:1660-8151

 

年代: 1984

 

DOI:10.1159/000183320

 

出版商: S. Karger AG

 

关键词: Cationic albumin;Proteinuria;Tubular damage;Urinary pH

 

数据来源: Karger

 

摘要:

40-mg doses of human cationic (CA) or anionic (AA) albumin were admistered intravenously to 48 normal female rats. Sodium bicarbonate (NaHCO3) was administered to 8 of these animals before CA or AA. Urine alkalinization caused increased renal CA excretion in CA-injected animals, which also showed marked reduction of the intensity of the renal changes produced by CA.

 

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