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Virus‐associated Hemophagocytic Syndrome Following Bone Marrow Transplantation

 

作者: David Reardon,   Rudolph Roskos,   Curtis Hanson,   Valerie Castle,  

 

期刊: American Journal of Pediatric Hematology/Oncology  （OVID Available online 1991）
卷期: Volume 13, issue 3  

页码: 305-309

 

ISSN:0192-8562

 

年代: 1991

 

出版商: OVID

 

关键词: Bone marrow transplantation;Graft-versushost disease;Natural killer cells;Immunodeficiency

 

数据来源: OVID

 

摘要:

Multiple-organ infiltration by mature, benign erythro-phagocytic histiocytes is the pathologic hallmark of the virus-associated hemophagocytic syndrome (VAHS). Although VAHS has been described in a number of clinical settings, it has been reported following bone marrow transplantation (BMT) only once previously. Our report identifies the clinical and laboratory features associated with VAHS and compares the immune defects described in VAHS with those known to occur following BMT.

 

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