Interpreting murine tolerance experiments
作者:
Joel Trambley,
Thomas Pearson,
Christian Larsen,
期刊:
Current Opinion in Organ Transplantation
(OVID Available online 2000)
卷期:
Volume 5,
issue 2
页码: 103-107
ISSN:1087-2418
年代: 2000
出版商: OVID
数据来源: OVID
摘要:
Murine allograft models have been a major tool in the quest for transplantation tolerance. As the search for tolerance shifts toward larger animal models and humans, it becomes critical to determine which of the successful murine strategies hold the most promise for broad application. This requires clear criteria for treatment goals and a paradigm for meaningful comparison of the various organs, strains, and treatments used in the murine system.
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