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Pyridine nucleotide oxidation‐reduction state of the cerebral cortex in the awake gerbil

 

作者: Avraham Mayevsky,  

 

期刊: Journal of Neuroscience Research  （WILEY Available online 1978）
卷期: Volume 3, issue 5‐6  

页码: 369-374

 

ISSN:0360-4012

 

年代: 1978

 

DOI:10.1002/jnr.490030508

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

关键词: brain energy metabolism;NADH oxidation‐reduction state;ischemia in gerbil's brain;spreading depression and NADH

 

数据来源: WILEY

 

摘要:

AbstractA new approach to study the effect of ischemia on the brain of the awake gerbil is described. The measurement of NADH fluorescence from the surface of the cortex is done by a time‐sharing fluorometer/reflectometer connected to the brain via a flexible light guide and an implanted cannula. The response of the gerbil brain to anoxia and spreading depression is described. By unilateral occlusion of the carotid artery and increase in NADH was measured in the ipsilateral hemispher

 

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