Pathway and regulation of JHIII‐bisepoxide biosynthesis in adultDrosophila melanogastercorpus allatum
作者:
Pnina Moshitzky,
Shalom W. Applebaum,
期刊:
Archives of Insect Biochemistry and Physiology
(WILEY Available online 1995)
卷期:
Volume 30,
issue 2‐3
页码: 225-237
ISSN:0739-4462
年代: 1995
DOI:10.1002/arch.940300211
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Drosophila melanogaster;corpus allatum;juvenile hormone;radiochemical assay;allatostatic factor
数据来源: WILEY
摘要:
AbstractAdult femaleDrosophila melanogastercorpus allatum (CA) synthesize JHB3from endogenous and exogenous precursors in vitro. We present evidence supporting the thesis that biosynthesis proceeds from precursor FA via initial epoxidation and terminal methylation on the basis of the following: (1) Methyl farnesoate is not epoxidized to JHIII or JHB3; (2) Authentic JHIII is not epoxidized to JHB3; and (3) FABE is markedly metabolized to JHB3. Cerebral allatostatic factors act at some stage subsequent to FA and this precursor is not normally rate‐limiting. Additionally, neural inhibition from the brain acts at some biosynthetic step prior to FA. © 1995 Wiley‐Liss,
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