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Treatment Options in Severe Psychotic Depression

 

作者: Arifulla,   Khan Seth,   Cohen Michelle,   Stowell Robin,   Capwell David,   Avery David,  

 

期刊: Convulsive Therapy  （OVID Available online 1987）
卷期: Volume 3, issue 2  

页码: 93-99

 

ISSN:0749-8055

 

年代: 1987

 

出版商: OVID

 

关键词: Delusional depression;Depressive disorder;Affective disorders, psychotic;Electroconvulsive therapy;Antidepressive agents, tricyclic;Tranquilizing agent, major;Outcome assessment

 

数据来源: OVID

 

摘要:

In our sample of 15 hospitalized patients with severe psychotic depression, six responded to therapy with tricyclic antidepressants combined with neuroleptics. Of the nine nonresponders, eight showed an excellent clinical response to electroconvulsive therapy (ECT). The clinical outcome after 6 months of treatment was similar in both groups. We recommend that protracted, complicated trials of pharmacotherapy be reevaluated in psychotic depression. A prospective comparative study of ECT and pharmacotherapy is needed to define the optimal treatment for psychotic depression.

 

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