Inheritance of atrioventricular conduction time in Tokelau Islanders
作者:
L. H. Griggs,
C. J. Chapman,
D. J. McHaffie,
期刊:
Clinical Genetics
(WILEY Available online 1986)
卷期:
Volume 29,
issue 1
页码: 56-61
ISSN:0009-9163
年代: 1986
DOI:10.1111/j.1399-0004.1986.tb00771.x
出版商: Blackwell Publishing Ltd
关键词: A‐V conduction;segregation analysis;Tokelau
数据来源: WILEY
摘要:
The inheritance of A‐V conduction time in Polynesians has been examined, using ECGs taken from the population of the Tokelau Islands. As has been demonstrated in other racial groups, A‐V conduction time was influenced by sex, age, and heart rate.Complex segregation analysis provides evidence for a significant polygenic influence on A‐V conduction, but no evidence for a major gene. Familial correlations and commingling analysis are in agreement with this conclusion. The heritability of A‐V conduction time was 0.46.The hypothesis of M0ller&Heiberg (1980a) that a major gene could be influencing A‐V conduction, is not supported by t
点击下载:
PDF
(372KB)
返 回