Immunopathogenesis of HIV Infection
作者:
Hans Wigzell,
期刊:
Journal of Acquired Immune Deficiency Syndromes
(OVID Available online 1988)
卷期:
Volume 1,
issue 6
页码: 559-565
ISSN:0894-9255
年代: 1988
出版商: OVID
关键词: HIV;CD4-positive cells;T cell;Enhancement
数据来源: OVID
摘要:
Summary:HIV may cause CD4-positive T cell depletion not only by direct infection but by causing damage to normal maintenance mechanisms. Findings in support of such a concept are presented. Results suggesting that immune reactions against HIV may contain elements of a negative nature are presented, in particular in relation to viral enhancement by antibodies. A question is also raised whether HIV replication has been proved to be reduced in a significant manner by immune reactions.
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