A brief overview of analytical chemistry research in Australia is presented and reference is made to the work of several research groups. Topics covered include the development of a longitudinally modulated cryogenic system for comprehensive gas chromatography, mixed-mode capillary electrochromatography for manipulation of separation selectivity of inorganic ions, new developments in chemical metrology, discontinuous flow analysis and its applications, the design and applications of an orthogonal acceleration time-of-flight mass spectrometer, and the use of chemiluminescence in a range of analytical techniques.