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Does Fibronect in Influence the Determination of Circulating Immune Complexes by Means of a Clq-Enzyme Immunoassay?

 

作者: Werner SchöBler,   Falk Hiepe,   Ansgar Lukowsky,  

 

期刊: Analytical Letters  （Taylor Available online 1985）
卷期: Volume 18, issue 7  

页码: 847-854

 

ISSN:0003-2719

 

年代: 1985

 

DOI:10.1080/00032718508066182

 

出版商: Taylor & Francis Group

 

关键词: fibronectin;enzyme immunoassay;circulating immune complexes

 

数据来源: Taylor

 

摘要:

Fibronect in was shown to bind to solid-phase C1q and to inhibit the binding of aggregated lgG in an C1q-solid-phase enzyme immunoassay in the absence of human serum. In the presence of human serum the determination of aggregated lgG and circulating immune complexes is not influenced by fibronectin in this assay. Therefore, we suggest that fibronectin does not affect the determination of immune complexes in serum specimens by C1q binding assays.

 

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