ABSTRACT:Two scenarios of CO2‐induced climatic change are used to estimate changes in water use for a number of municipalities in the Great Lakes region of Canada and the United States. Both scenarios, based on General Circulation Models produced by the Goddard Institute for Space Studies (GISS) and Geophysical Fluid Dynamics Lab (GFDL), project warmer temperatures for the region. Using regression models based on monthly potential evapotranspiration for individual cities, it is projected that annual per capita water use will increase by a small amount, which will probably have only a marginal effect on water supplies in the Great Lakes basin. This method could also be used to assess the potential impacts of CO2‐induced climatic change on water use by the agriculture and power sectors, as well as the effectiveness of water policy initiatives, such as price changes. More work is needed to project water use during peak periods (warm dry spells), which may occur more frequently in a 2 × CO2climate in this re