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Family Distances as a Measure of Hidden Consanguinity

 

作者: Janny Swaving,   Alex Groenewegen,   Aukje Kamstra,   Gerard J. te Meerman,   Leo P. ten Kate,  

 

期刊: Human Heredity  （Karger Available online 1991）
卷期: Volume 41, issue 1  

页码: 12-16

 

ISSN:0001-5652

 

年代: 1991

 

DOI:10.1159/000153967

 

出版商: S. Karger AG

 

关键词: Autosomal recessive disorders;Consanguinity;Family distances;Genealogy

 

数据来源: Karger

 

摘要:

We compared the family distances of patients with autosomal recessive disorders with those of a random control group and a matched control group. Only in the great-grandparental generation were weak-significant differences found. We also found that the family distances of persons with an urban origin were significantly larger than those of persons with a rural origin. In our study, family distance seems to be a more powerful measure of hidden consanguinity than the parental distance.

 

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