Imaging of single‐stranded DNA with the scanning tunneling microscope
作者:
A. Cricenti,
S. Selci,
G. Chiarotti,
F. Amaldi,
期刊:
Journal of Vacuum Science&Technology B: Microelectronics and Nanometer Structures Processing, Measurement, and Phenomena
(AIP Available online 1991)
卷期:
Volume 9,
issue 2
页码: 1285-1287
ISSN:1071-1023
年代: 1991
DOI:10.1116/1.585222
出版商: American Vacuum Society
关键词: DNA;ORGANIC COMPOUNDS;MIXTURES;GOLD;SUBSTRATES;IMAGES;SCANNING TUNNELING MICROSCOPY;HIGH−RESOLUTION METHODS
数据来源: AIP
摘要:
Uncoated single‐strand DNA mixed with BAC (benzyldimethylalkylammonium chloride) were deposited on gold substrates and imaged in air with the use of a high‐resolution scanning tunneling microscope (STM). Constant‐current and gap‐modulated STM images showed both double‐ and single‐stranded DNA. Along the single DNA backbone we have, tentatively, assigned small structures to phosphate and sugar group components; bumps aside single filaments, that correspond, presumably, to the bases of DNA, have sometimes been observed.
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