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Gastric Electric Activity Assessed by Electrogastrography and Gastric Emptying Scintigraphy in Adolescents With Eating Disorders

 

作者: A. Diamanti,   F. Bracci,   M. Gambarara,   G. Ciofetta,   T. Sabbi,   A. Ponticelli,   F. Montecchi,   S. Marinucci,   G. Bianco,   M. Castro,  

 

期刊: Journal of Pediatric Gastroenterology and Nutrition  (OVID Available online 2003)
卷期: Volume 37, issue 1  

页码: 35-41

 

ISSN:0277-2116

 

年代: 2003

 

出版商: OVID

 

关键词: Eating disorders;Anorexia nervosa;Bulimia nervosa;Gastric electric activity;Gastric emptying

 

数据来源: OVID

 

摘要:

Background:Patients with eating disorders can refer to a variety of gastrointestinal symptoms, sometimes to justify reduced food intake and vomiting. The authors investigated whether adolescent patients with eating disorders and dyspeptic symptoms have altered gastric electric activity and abnormal gastric emptying as assessed respectively by electrogastrography and scintigraphy.Methods:Twenty‐eight patients (18 with anorexia and 10 with bulimia) and 16 healthy volunteers underwent electrogastrography; 20 of the 28 patients (14 with anorexia and 6 with bulimia) underwent gastric emptying scintigraphy. Electrogastrography with bipolar recording lasted 1 hour, 30 minutes before and after a standard meal. Before gastric emptying scintigraphy, patients fasted overnight; during testing, they ingested a solid meal labeled with technetium‐99m sulfur colloid. The ratio of fasting to postprandial electrogastrographic variables was evaluated using the Wilcoxon matched‐pair test. The Mann‐Whitney test was used to compare absolute values for electrogastrographic data in each group. The Student pairedttest was used to compare scintigraphic results expressed as percentage of gastric emptying at 60 minutes and as the gastric emptying time (T½).Results:Patients with bulimia significantly differed from those with anorexia and control subjects regarding the amount of normal gastric electric activity and bradygastria, and from patients with anorexia only regarding tachygastria. These electrogastrographic variables did not differ significantly between patients with anorexia and control subjects. Gastric emptying time (T½) was significantly longer in patients with bulimia than in those with anorexia.Conclusions:Adolescent patients with bulimia who complain of dyspeptic symptoms have documentable abnormalities of gastric electric activity and emptying, whereas their counterparts with anorexia, probably owing to their shorter disease duration, do not.

 

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