Synthesis and antimalarial effects of [1]benzothieno[3,2‐f]quinazoline‐1,3‐diamine
作者:
Judith Johnson,
Edward F. Elslager,
Leslie M. Werbel,
期刊:
Journal of Heterocyclic Chemistry
(WILEY Available online 1977)
卷期:
Volume 14,
issue 7
页码: 1209-1214
ISSN:0022-152X
年代: 1977
DOI:10.1002/jhet.5570140716
出版商: Wiley‐Blackwell
数据来源: WILEY
摘要:
AbstractBromination of 2‐dibenzothiophenamine has been shown to afford 1‐bromo‐2‐dibenzothio‐phenamine rather than the previously reported 3‐isomer. This material was converted to the 1‐cyano derivative and cyclized with chloroformamidine hydrochloride to [l]benzothieno‐[3,2‐f]quinazoline‐1,3‐diamine. Both this and the corresponding 7,7‐dioxide were devoid o
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