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Synthesis and antimalarial effects of [1]benzothieno[3,2‐f]quinazoline‐1,3‐diamine

 

作者: Judith Johnson,   Edward F. Elslager,   Leslie M. Werbel,  

 

期刊: Journal of Heterocyclic Chemistry  (WILEY Available online 1977)
卷期: Volume 14, issue 7  

页码: 1209-1214

 

ISSN:0022-152X

 

年代: 1977

 

DOI:10.1002/jhet.5570140716

 

出版商: Wiley‐Blackwell

 

数据来源: WILEY

 

摘要:

AbstractBromination of 2‐dibenzothiophenamine has been shown to afford 1‐bromo‐2‐dibenzothio‐phenamine rather than the previously reported 3‐isomer. This material was converted to the 1‐cyano derivative and cyclized with chloroformamidine hydrochloride to [l]benzothieno‐[3,2‐f]quinazoline‐1,3‐diamine. Both this and the corresponding 7,7‐dioxide were devoid o

 

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