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Diabetic end stage renal failure – the Wellington experience 1975–1988

 

作者: T. J. Thompson,   M. Fisher,   P. J. Hatfield,   R. B. I. Morrison,   T. J. Neale,  

 

期刊: Australian and New Zealand Journal of Medicine  (WILEY Available online 1991)
卷期: Volume 21, issue 1  

页码: 29-35

 

ISSN:0004-8291

 

年代: 1991

 

DOI:10.1111/j.1445-5994.1991.tb02998.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Diabetes;end stage renal failure;Maori

 

数据来源: WILEY

 

摘要:

Abstract:Since the late 1970s patients with diabetic nephropathy have formed an increasing proportion of new entrants to the Hospital renal dialysis and transplantation programme, reaching 28% for the three year period to December 1988. Between 1 January 1975 and 31 December 1988, 87 diabetic patients were accepted for treatment. Fifty‐one per cent were European, predominantly type I diabetics. Maori (9% of the total reference population) accounted for a disproportionately high 47% due to an over‐representation by type II diabetic patients (34 of 41 Maori). These findings cannot be explained by the higher prevalence in Maori of type II diabetes but appear to be due to a more prevalent and/or aggressive diabetic renal lesion in this group. On commencing treatment, nearly all patients had retinopathy and the majority had evidence of peripheral vascular disease, hypertension and neuropathy. CAPD was the initial mode of renal replacement therapy in 70% of patients. Overall patient survival was 77% at one year and 42% at three years, and survival on CAPD was 76% and 37% at one and three years, respectively. Patient survival on transplantation was 63% at one year and 58% at three years. Graft survival was 51% at one year and 46% at three years. Although the short term outlook for diabetic patients on renal replacement therapy is encouraging, longer term survival compared to non‐diabetic patients is poor. Vascular disease is the major cause of death and an important factor in patient morb

 

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