Primary Sarcoma of the Adult VaginaA Clinicopathologic Study
作者:
WILLIAM PETERS,
NEELAM KUMAR,
WILLIE ANDERSEN,
GEORGE MORLEY,
期刊:
Obstetrics & Gynecology
(OVID Available online 1985)
卷期:
Volume 65,
issue 5
页码: 699-704
ISSN:0029-7844
年代: 1985
出版商: OVID
数据来源: OVID
摘要:
Combination chemotherapy has dramatically improved the results of treatment for embryonal rhabdomyosarcoma of the vagina in children, but little attention has been directed toward vaginal sarcomas in adults. This report of 17 cases of primary sarcoma of the adult vagina includes ten leiomyosarcomas, four mixed mesodermal tumors, one undifferentiated sarcoma, one stromal sarcoma, and one neurofibrosarcoma. The leiomyosarcomas, mixed mesodermal tumors, and the stromal sarcoma were morphologically similar to their uterine counterparts. Thirty-five percent of the patients had received pelvic irradiation for carcinoma of the cervix. Three of four patients treated by pelvic exenteration are alive and disease free after 84 to 161 months of observation. All 13 patients who received other forms of primary therapy died of recurrence. The pelvis was the first site of recurrence in all treatment failures and the only site of failure in 50%.
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