SummaryA fatal case of influenza is described. The 57 Singapour virus could be isolated. Post-mortem examination showed extensive bilateral bronchopneumonia, with bronchiolitis, bronchitis and ulcerative tracheitis. Cultures of autopsy material and bronchial secretions yielded a Staphylococcus aureus strain which was sensitive in vitro to currently used antibiotics. There were also important pleural effusions which remained sterile on culture.The fulminating course of the disease did not permit any recording of original laboratory data and the case seems quite common when it is properly situated in the literature. Nevertheless, it was thought that it could be interesting to compare it with those published by others.The therapeutic management of such cases is discussed.