Evidence for the Existence of Atrial Natriuretic Factor-Containing Neurons in the Rat Brain
作者:
David M. Jacobowitz,
Gerhard Skofitsch,
Harry R. Keiser,
Robert L. Eskay,
Nadav Zamir,
期刊:
Neuroendocrinology
(Karger Available online 1985)
卷期:
Volume 40,
issue 1
页码: 92-94
ISSN:0028-3835
年代: 1985
DOI:10.1159/000124058
出版商: S. Karger AG
关键词: Immunohistochemistry;Brain;Atrial natriuretic factor
数据来源: Karger
摘要:
Immunoreactive atrial natriuretic factor- (ANF-)positive nerve fibers and cell bodies were observed in the preoptic area, hypothalamus, mesencephalon, and pons of rats. In colchicine-treated animals a large number of immunoreactive ANF-positive cell bodies were seen in the organum vasculosum of the lamina terminalis, in several hypothalamic nuclei (e.g. periventricular, arcuate, and ventral premammillary nuclei), and in the dorsolateral tegmental nuclei of the pons. Varicose nerve fibers containing ANF were generally observed in the vicinity of the cells. These findings indicate that a widespread network of ANF-containing neurons is present in the brain.
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