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COX 2a promising target for chemotherapy

 

作者: Robert Carlson,  

 

期刊: Inpharma Weekly  (ADIS Available online 1999)
卷期: Volume &NA;, issue 1195  

页码: 9-10

 

ISSN:1173-8324

 

年代: 1999

 

出版商: ADIS

 

数据来源: ADIS

 

摘要:

Inhibition of cyclo-oxygenase 2 (COX 2) may represent a potential anti-cancer strategy. It has already been observed that people who receive long-term therapy with NSAIDs (typically for arthritis) have a lower incidence of colon cancer.*Data presented at the 35th Annual Meeting of the American Society of Clinical Oncology, [Atlanta, US; May 1999], confirm the COX 2/bcl-2 gene connection, and suggest how a COX 2 inhibitor may fit into the current antineoplastic armamentarium.

 

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