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Distribution and effects of intravenous lead in the fetoplacental unit of the rat

 

作者: P. L. Hackett,   J. O. Hess,   M. R. Sikov,  

 

期刊: Journal of Toxicology and Environmental Health  （Taylor Available online 1982）
卷期: Volume 9, issue 5-6  

页码: 1021-1032

 

ISSN:0098-4108

 

年代: 1982

 

DOI:10.1080/15287398209530222

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

Lead metabolism was studied in the fetoplacental unit (FPU) of Wistar rats during the genesis of developmental abnormalities and embryonic death. Female rats were injected iv with tracer210Pb(NO3)2, alone or in combination with 5 or 25 mg Pb(NO3)2/kg, at 9 or 15 days of gestation (dg). The distribution of lead and its effects were determined in the FPUs during the ensuing 30‐h period and at 20 dg.

 

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