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Effect of Acetazolamide on the Insulin Response to Intravenous Administration of Secretin

 

作者: S. Raptis,   H. Dollinger,   G. Rothenbuchner,   R. Fussgänger,   U. Klör,   E.F. Pfeiffer,  

 

期刊: Annals of Nutrition and Metabolism  （Karger Available online 1974）
卷期: Volume 16, issue 2  

页码: 79-86

 

ISSN:0250-6807

 

年代: 1974

 

DOI:10.1159/000175475

 

出版商: S. Karger AG

 

关键词: Secretin;Exocrine pancreas;Endocrine pancreas;Acetazolamide;Insulin

 

数据来源: Karger

 

摘要:

In 15 subjects, secretin administered intravenously increased the insulin secretion significantly as well as volume and bicarbonate content of the duodenal juice. The inhibition of the exocrine pancreas by acetazolamide did not influence the β-cytotropic effect of secretin. The loss of this effect in patients suffering from chronic pancreatic insufficiency seems, therefore, to be caused, not by the decreased volume and bicarbonate secretion, butby other unknown factors

 

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