Ki-1-Positive Anaplastic Large Cell Lymphoma with Different Phenotypes in Skin Nodules and Lymph Nodes
作者:
K. Oka,
T. Matsumoto,
期刊:
Dermatology
(Karger Available online 1994)
卷期:
Volume 188,
issue 1
页码: 52-56
ISSN:1018-8665
年代: 1994
DOI:10.1159/000247087
出版商: S. Karger AG
关键词: Ki-1-positive anaplastic large cell lymphoma;Ber-H2 (CD30);KP1 (CD68);MAC387;LN-5
数据来源: Karger
摘要:
A 54-year-old man had lymph node swelling and skin nodules. Neoplastic cells with pleomorphic nuclei, prominent eosinophilic nucleoli and abundant cytoplasm were present in the lymph node sinuses and around the dermal appendages. Neoplastic cells in the lymph nodes expressed Ber-H2 (CD30)+/KP1 (CD68)+/MAC387–/LN-5+. Those in the skin nodules expressed Ber-H2+/KP1–/MAC387+/LN-5–. These findings suggest that he had Ki-1-positive anaplastic large cell lymphoma (ALCL) with different phenotypes in lymph nodes and skin nodules. The discrepancy among KP1, MAC387 and LN-5 reactivities may represent the concurrent occurrence of ALCL and lymphomatoid papulosis. However, the possibility cannot be ruled out that ALCL developed first in the lymph nodes and then metastasized to the
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