Stage IA1Cervical AdenocarcinomaDefinition and Treatment
作者:
JOHN SCHORGE,
KENNETH LEE,
CYNTHIA FLYNN,
ANNEKATHRYN GOODMAN,
ELLEN SHEETS,
期刊:
Obstetrics & Gynecology
(OVID Available online 1999)
卷期:
Volume 93,
issue 2
页码: 219-222
ISSN:0029-7844
年代: 1999
出版商: OVID
数据来源: OVID
摘要:
ObjectiveTo propose a definition for stage IA1cervical adenocarcinoma, based on the International Federation of Gynecology and Obstetrics (FIGO) staging system, and to determine if patients meeting criteria might be candidates for conservative surgery.MethodsTwo hundred women were diagnosed with early-stage cervical adenocarcinoma from 1982 to 1996. Histopathologic sections were reviewed by a gynecologic pathologist. Medical records were reviewed, and patients included in this study had microscopically identifiable lesions, up to 3 mm invasive depth, up to 7 mm tumor width, and negative margins if cone biopsy was performed.ResultsTwenty-one patients with microinvasive adenocarcinoma met criteria for FIGO stage IA1carcinoma of the cervix. The median (range) follow-up was 76 (30–172) months and median (range) patient age was 38 (24–75) years. Definitive treatment included type II or III radical hysterectomy in 16 cases, simple abdominal or vaginal hysterectomy in four cases, and loop electrosurgical excision procedure in one case; one patient received adjuvant pelvic radiation. The histologic subtypes were endocervical adenocarcinoma in 18 cases, adenosquamous carcinoma in two cases, and clear-cell adenocarcinoma in one case. There was no evidence of parametrial invasion or lymph node metastases in any patient who had radical surgery, and there were no disease recurrences.ConclusionPatients with microinvasive adenocarcinoma who met criteria for FIGO stage IA1cervical carcinoma had disease limited to the cervix, and conservative surgery, such as cone biopsy or simple hysterectomy, might offer them definitive treatment.
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