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Synthesis of an Acyloxymethyl Prodrug of the Inositol Phosphate α-Trinositol

 

作者: Anneli Lindahl,   Mats Malmberg,   Nicola Rehnberg,  

 

期刊: Journal of Carbohydrate Chemistry  (Taylor Available online 1996)
卷期: Volume 15, issue 5  

页码: 549-554

 

ISSN:0732-8303

 

年代: 1996

 

DOI:10.1080/07328309608005673

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

Acyloxymethylation of an acylated silver salt of α-trinositol gives, after deprotection, membrane permeable 1D-myo-inositol 1,2,6-tris(ethoxycarbonyloxymethyl sodium phosphate). The acyl groups, 3-(4,5-methylenedioxy-2-nitrophenyl)propanoyl, are cleaved by hydrogenolysis.

 

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