Efficacy of Bufexamac (NFN) Cream in Skin Diseases
作者:
J.V. Christiansen,
E. Gadborg,
I. Kleiter,
K. Ludvigsen,
C.H.K. Meier,
A. Nørholm,
H. Reiter,
F. Reymann,
W. Raaschou-Nielsen,
M. Søndergaard,
P. Unna,
R. Wehnert,
期刊:
Dermatology
(Karger Available online 1977)
卷期:
Volume 154,
issue 3
页码: 177-184
ISSN:1018-8665
年代: 1977
DOI:10.1159/000251127
出版商: S. Karger AG
关键词: Anti-inflammatory cream in skin diseases;Bufexamac;Multicentre trial
数据来源: Karger
摘要:
The effect of a new non-steroid anti-inflammatory substance (bufexamac) in a special constituent was compared with that of 0.1% triamcinolone acetonide, 1% hydrocortisone cream, and placebo during a double-blind multicentre trial. The clinical effect of these four creams was studied in 193 patients receiving treatment for the following skin disorders: atopic dermatitis, allergic contact dermatitis, and non-allergic contact dermatitis, as well as dermatitis seborrheica. After 2 and 4 weeks’ treatment, when 193 and 157 patients, respectively, were re-examined, the effect of triamcinolone acetonide and hydrocortisone cream was significantly better, than that obtained with bufexamac in the cream basis employed. On the other hand, no statistically significant difference in effect between bufexamac and placebo cream was observe
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