Somatostatin immunoreactivity in bone and joint tissues
作者:
Adlan Elhassan,
Abdu Adem,
K Hultenby,
J Lindgren,
期刊:
NeuroReport
(OVID Available online 1998)
卷期:
Volume 9,
issue 11
页码: 2573-2575
ISSN:0959-4965
年代: 1998
出版商: OVID
关键词: Bone;Myelinated nerve;Periosteum;Somatostatin
数据来源: OVID
摘要:
USING immunoelectron microscopy we have investigated the presence of somatostatin in normal bone and joint tissues. We observed somatostatin labeling in the myelinated nerve fibers of the periosteum, the bone marrow cells and in the mature bone matrix but only slightly in the synovial cells. Quantification of somatostatin in bone tissue by radioimmunoassay showed highest levels in bone marrow followed by periosteum and cortical bone. These findings suggest a role for somatostatin in bone and joint physiology.
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