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Amplification of themetgene in glioma

 

作者: Ulrike Fischer,   Hans‐W. Müller,   Hans‐P. Sattler,   Klaus D. Zang,   Eckart Meese,   Klaus Feiden,  

 

期刊: Genes, Chromosomes and Cancer  （WILEY Available online 1995）
卷期: Volume 12, issue 1  

页码: 63-65

 

ISSN:1045-2257

 

年代: 1995

 

DOI:10.1002/gcc.2870120111

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractWe have previously reported the finding ofMETamplification linked to double minutes (dmins) in a human glioblastoma (TX3095). Because dmins are found in approximately 50% of glioblastomas, 18 gliomas were analyzed forMETamplification. Three grade IV glioblastomas and one grade II astrocytoma showed amplification. We could also localize theMETamplicon to dmins in glioblastoma TX3095 by fluorescence in situ hybridization.

 

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