An Analysis of the One-Stage Prothrombin Time
作者:
Ingebrigt Talstad,
期刊:
Pathophysiology of Haemostasis and Thrombosis
(Karger Available online 1985)
卷期:
Volume 15,
issue 5
页码: 310-317
ISSN:1424-8832
年代: 1985
DOI:10.1159/000215165
出版商: S. Karger AG
关键词: Blood coagulation tests;Liver function tests;Prothrombin time;Warfarin
数据来源: Karger
摘要:
An analysis of the one-stage prothrombin time using thromboplastins highly (Thrombotest®) and slightly (Normotest®) sensitive to the Pivka (protein induced by vitamin K absence) inhibitor is presented. A one-tenth dilution of blood with 0.1 mol/l Na3 citrate was satisfactory even at an extreme packed cell volume (PCV). Whole blood and plasma were equally satisfactory as test materials; however, their accuracy and precision were greatly improved when a small sample size at a high coagulation activity and a large sample size at a low coagulation activity were used. The PCV correction method which corrected for the different Pivka inhibitor sensitivities of thromboplastins was preferabl
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